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Two men and two boys were arrested by the Neighbourhood Policing Team in Dukinfield over the supply of Class A, B and C drugs in the town.
Police visited an address to arrest a wanted man. The suspect was not at the address but a large amount of drugs, cash, scales and mobile phones were found.
As a result, two other addresses were raided and searched and the four were arrested.
A Tameside police spokesman said: "This was a great result for the Neighbourhood Team."
If you have any information about the drug supply in Tameside – please contact your local Neighbourhood Team via Bee in the loop, calling 101 (999 if you are in danger) or report anonymously via Crimestoppers.