Raids at seven properties across Oldham, other parts of Greater Manchester and Buckinghamshire saw six people arrested and a suspected cannabis farm seized.
At around 5.30am on Thursday morning (17 June), officers from Greater Manchester Police's Tactical Aid Unit (TAU) and Serious and Organised Crime Group (SOCG) raided properties in Oldham, as well as Bury, Milnrow, Radcliffe, Farnworth and Crumpsall.
A suspected cannabis farm comprising of 18 plants was found in Radcliffe and cannabis cultivation equipment was also recovered at the Farnworth address.
Five people - three women and two men aged between 25 and 42 - were arrested on suspicion of conspiracy to supply cocaine and cannabis.
An address in the Gerrards Cross area of Buckinghamshire was also visited, and a 54-year-old man was arrested on suspicion of conspiracy to supply class A drugs.
The suspects have all being taken to custody for questioning in relation to an investigation by GMP's Serious and Organised Crime Group into a class A and B drugs conspiracy that detectives estimate to be worth millions of pounds.
Investigators launched the operation - codenamed Glory - in June 2020 as part of a probe into the supply of class A drugs across Greater Manchester, and beyond, by individuals with links to organised crime.
Detective Chief Inspector Joe Harrop, of GMP's Serious Crime Division, said: "Today we have targeted a number of suspects that we believe are involved in the mass supply of class A and B drugs, namely cocaine and cannabis not just in Greater Manchester but across the North West.
"Action like this comes after months of hard work to collate evidence and ensure we are tackling those responsible, but a huge part of our initial intelligence comes from members of the public feeding information to us or Crimestoppers anonymously.
"We will always encourage the community to come to us with any suspicions or information they have so that we can respond and remove suspects and their illicit assets from the streets, and drive a wedge between offenders the supply."
Anyone with information or concerns should contact police online, if able, via www.gmp.police.uk or call 101. Details can be passed anonymously to the independent charity Crimestoppers on 0800 555 111.
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